Natural product-inspired synthesis of coumarin–chalcone hybrids as potential anti-breast cancer agents

Twelve novel neo-tanshinlactone–chalcone hybrid molecules were constructed through a versatile methodology involving the Horner–Wadsworth–Emmons (HWE) olefination of 4-formyl-2H-benzo [h]chromen-2-ones and phosphonic acid diethyl esters, as the key step, and evaluated for anticancer activity against...

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Detalles Bibliográficos
Autores principales: Alhakamy, Nabil A., Saquib, Mohammad, Sanobar, Khan, Mohammad Faheem, Ansari, Waseem Ahmad, Arif, Deema O., Irfan, Mohammad, Khan, Mohammad Imran, Hussain, Mohd Kamil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511752/
https://www.ncbi.nlm.nih.gov/pubmed/37745072
http://dx.doi.org/10.3389/fphar.2023.1231450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511752/
https://www.ncbi.nlm.nih.gov/pubmed/37745072
http://dx.doi.org/10.3389/fphar.2023.1231450

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