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Uniformly shaped harmonization combines human transcriptomic data from different platforms while retaining their biological properties and differential gene expression patterns

Introduction: Co-normalization of RNA profiles obtained using different experimental platforms and protocols opens avenue for comprehensive comparison of relevant features like differentially expressed genes associated with disease. Currently, most of bioinformatic tools enable normalization in a fl...

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Detalles Bibliográficos
Autores principales: Borisov, Nicolas, Tkachev, Victor, Simonov, Alexander, Sorokin, Maxim, Kim, Ella, Kuzmin, Denis, Karademir-Yilmaz, Betul, Buzdin, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511763/
https://www.ncbi.nlm.nih.gov/pubmed/37745690
http://dx.doi.org/10.3389/fmolb.2023.1237129