Solution structure of the HOIL-1L NZF domain reveals a conformational switch regulating linear ubiquitin affinity

Attachment of polyubiquitin (poly-Ub) chains to proteins is a major posttranslational modification in eukaryotes. Linear ubiquitin chain assembly complex, consisting of HOIP (HOIL-1-interacting protein), HOIL-1L (heme-oxidized IRP2 Ub ligase 1), and SHARPIN (Shank-associated RH domain–interacting pr...

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Detalles Bibliográficos
Autores principales: Walinda, Erik, Sugase, Kenji, Ishii, Naoki, Shirakawa, Masahiro, Iwai, Kazuhiro, Morimoto, Daichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511788/
https://www.ncbi.nlm.nih.gov/pubmed/37595872
http://dx.doi.org/10.1016/j.jbc.2023.105165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511788/
https://www.ncbi.nlm.nih.gov/pubmed/37595872
http://dx.doi.org/10.1016/j.jbc.2023.105165

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