Single-nucleus RNA-sequencing reveals NRF1/NFE2L1 as a key factor determining the thermogenesis and cellular heterogeneity and dynamics of brown adipose tissues in mice

Brown adipose tissue (BAT) is a major site of non-shivering thermogenesis in mammals and plays an important role in energy homeostasis. Nuclear factor-erythroid 2-related factor 1 (NFE2L1, also known as Nrf1), a master regulator of cellular metabolic homeostasis and numerous stress responses, has be...

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Detalles Bibliográficos
Autores principales: Shen, Wei, Ren, Suping, Hou, Yongyong, Zuo, Zhuo, Liu, Shengnan, Liu, Zhiyuan, Fu, Jingqi, Wang, Huihui, Yang, Bei, Zhao, Rui, Chen, Yanyan, Yamamoto, Masayuki, Xu, Yuanyuan, Zhang, Qiang, Pi, Jingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511808/
https://www.ncbi.nlm.nih.gov/pubmed/37716088
http://dx.doi.org/10.1016/j.redox.2023.102879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511808/
https://www.ncbi.nlm.nih.gov/pubmed/37716088
http://dx.doi.org/10.1016/j.redox.2023.102879

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