MAPK13 stabilization via m(6)A mRNA modification limits anticancer efficacy of rapamycin

N(6)-adenosine methylation (m(6)A) is the most abundant mRNA modification that controls gene expression through diverse mechanisms. Accordingly, m(6)A-dependent regulation of oncogenes and tumor suppressors contributes to tumor development. However, the role of m(6)A-mediated gene regulation upon dr...

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Detalles Bibliográficos
Autores principales: Kim, Joohwan, Chun, Yujin, Ramirez, Cuauhtemoc B., Hoffner, Lauren A., Jung, Sunhee, Jang, Ki-Hong, Rubtsova, Varvara I., Jang, Cholsoon, Lee, Gina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511813/
https://www.ncbi.nlm.nih.gov/pubmed/37599001
http://dx.doi.org/10.1016/j.jbc.2023.105175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511813/
https://www.ncbi.nlm.nih.gov/pubmed/37599001
http://dx.doi.org/10.1016/j.jbc.2023.105175

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