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MAPK13 stabilization via m(6)A mRNA modification limits anticancer efficacy of rapamycin
N(6)-adenosine methylation (m(6)A) is the most abundant mRNA modification that controls gene expression through diverse mechanisms. Accordingly, m(6)A-dependent regulation of oncogenes and tumor suppressors contributes to tumor development. However, the role of m(6)A-mediated gene regulation upon dr...
Autores principales: | Kim, Joohwan, Chun, Yujin, Ramirez, Cuauhtemoc B., Hoffner, Lauren A., Jung, Sunhee, Jang, Ki-Hong, Rubtsova, Varvara I., Jang, Cholsoon, Lee, Gina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511813/ https://www.ncbi.nlm.nih.gov/pubmed/37599001 http://dx.doi.org/10.1016/j.jbc.2023.105175 |
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