Parameter estimation and identifiability analysis for a bivalent analyte model of monoclonal antibody-antigen binding

Surface plasmon resonance (SPR) is an extensively used technique to characterize antigen-antibody interactions. Affinity measurements by SPR typically involve testing the binding of antigen in solution to monoclonal antibodies (mAbs) immobilized on a chip and fitting the kinetics data using 1:1 Lang...

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Detalles Bibliográficos
Autores principales: Nguyen, Kyle, Li, Kan, Flores, Kevin, Tomaras, Georgia D., Dennison, S. Moses, McCarthy, Janice M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511885/
https://www.ncbi.nlm.nih.gov/pubmed/37549723
http://dx.doi.org/10.1016/j.ab.2023.115263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511885/
https://www.ncbi.nlm.nih.gov/pubmed/37549723
http://dx.doi.org/10.1016/j.ab.2023.115263

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