Identification of RAD51 foci in cancer-associated circulating cells of patients with high-grade serous ovarian cancer: association with treatment outcomes

OBJECTIVE: Fifty percent of patients with high-grade serous ovarian cancer harbor defects in the homologous recombination repair pathway. RAD51 foci form where DNA is damaged, indicating its involvement in repairing double-stranded breaks. High levels of RAD51 in ovarian cancer tissue have been asso...

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Detalles Bibliográficos
Autores principales: Alizzi, Zena, Saravi, Sayeh, Khalique, Saira, McDonald, Thirza, Karteris, Emmanouil, Hall, Marcia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511972/
https://www.ncbi.nlm.nih.gov/pubmed/37541687
http://dx.doi.org/10.1136/ijgc-2023-004483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511972/
https://www.ncbi.nlm.nih.gov/pubmed/37541687
http://dx.doi.org/10.1136/ijgc-2023-004483

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