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Gut virome-colonising Orthohepadnavirus genus is associated with ulcerative colitis pathogenesis and induces intestinal inflammation in vivo

OBJECTIVES: Ulcerative colitis (UC) is a chronic inflammatory disorder of unknown aetiology. Gut virome dysbiosis is fundamental in UC progression, although its role in the early phases of the disease is far from fully understood. Therefore, we sought to investigate the role of a virome-associated p...

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Detalles Bibliográficos
Autores principales: Massimino, Luca, Palmieri, Orazio, Facoetti, Amanda, Fuggetta, Davide, Spanò, Salvatore, Lamparelli, Luigi Antonio, D'Alessio, Silvia, Cagliani, Stefania, Furfaro, Federica, D'Amico, Ferdinando, Zilli, Alessandra, Fiorino, Gionata, Parigi, Tommaso Lorenzo, Noviello, Daniele, Latiano, Anna, Bossa, Fabrizio, Latiano, Tiziana, Pirola, Alessandra, Mologni, Luca, Piazza, Rocco Giovanni, Abbati, Danilo, Perri, Francesco, Bonini, Chiara, Peyrin-Biroulet, Laurent, Malesci, Alberto, Jairath, Vipul, Danese, Silvio, Ungaro, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511988/
https://www.ncbi.nlm.nih.gov/pubmed/36788014
http://dx.doi.org/10.1136/gutjnl-2022-328375