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Longitudinal decline in striatal dopamine transporter binding in Parkinson’s disease: associations with apathy and anhedonia

BACKGROUND: Motivational symptoms such as apathy and anhedonia are common in Parkinson’s disease (PD), respond poorly to treatment, and are hypothesised to share underlying neural mechanisms. Striatal dopaminergic dysfunction is considered central to motivational symptoms in PD but the association h...

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Detalles Bibliográficos
Autores principales: Costello, Harry, Yamamori, Yumeya, Reeves, Suzanne, Schrag, Anette-Eleonore, Howard, Robert, Roiser, Jonathan P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511995/
https://www.ncbi.nlm.nih.gov/pubmed/37221053
http://dx.doi.org/10.1136/jnnp-2022-330790