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Intra-FCY1: a novel system to identify mutations that cause protein misfolding

Protein misfolding is a common intracellular occurrence. Most mutations to coding sequences increase the propensity of the encoded protein to misfold. These misfolded molecules can have devastating effects on cells. Despite the importance of protein misfolding in human disease and protein evolution,...

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Detalles Bibliográficos
Autores principales: Quan, N., Eguchi, Y., Geiler-Samerotte, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512024/
https://www.ncbi.nlm.nih.gov/pubmed/37745845
http://dx.doi.org/10.3389/fgene.2023.1198203