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Impact of the TLR4 agonist BECC438 on a novel vaccine formulation against Shigella spp.

Shigellosis (bacillary dysentery) is a severe gastrointestinal infection with a global incidence of 90 million cases annually. Despite the severity of this disease, there is currently no licensed vaccine against shigellosis. Shigella’s primary virulence factor is its type III secretion system (T3SS)...

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Detalles Bibliográficos
Autores principales: Lu, Ti, Das, Sayan, Howlader, Debaki R., Jain, Akshay, Hu, Gang, Dietz, Zackary K., Zheng, Qi, Ratnakaram, Siva Sai Kumar, Whittier, Sean K., Varisco, David J., Ernst, Robert K., Picking, William D., Picking, Wendy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512073/
https://www.ncbi.nlm.nih.gov/pubmed/37744341
http://dx.doi.org/10.3389/fimmu.2023.1194912