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Comprehensive profiling of pre-infection antibodies identifies HIV targets associated with viremic control and viral load

BACKGROUND: High HIV viral load (VL) is associated with increased transmission risk and faster disease progression. HIV controllers achieve viral suppression without antiretroviral (ARV) treatment. We evaluated viremic control in a community-randomized trial with >48,000 participants. METHODS: A...

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Detalles Bibliográficos
Autores principales: Grant-McAuley, Wendy, Morgenlander, William, Hudelson, Sarah E., Thakar, Manjusha, Piwowar-Manning, Estelle, Clarke, William, Breaud, Autumn, Blankson, Joel, Wilson, Ethan, Ayles, Helen, Bock, Peter, Moore, Ayana, Kosloff, Barry, Shanaube, Kwame, Meehan, Sue-Ann, van Deventer, Anneen, Fidler, Sarah, Hayes, Richard, Ruczinski, Ingo, Kammers, Kai, Laeyendecker, Oliver, Larman, H. Benjamin, Eshleman, Susan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512082/
https://www.ncbi.nlm.nih.gov/pubmed/37744365
http://dx.doi.org/10.3389/fimmu.2023.1178520