Burden Imposed by Heterologous Protein Production in Two Major Industrial Yeast Cell Factories: Identifying Sources and Mitigation Strategies

Production of heterologous proteins, especially biopharmaceuticals and industrial enzymes, in living cell factories consumes cellular resources. Such resources are reallocated from normal cellular processes toward production of the heterologous protein that is often of no benefit to the host cell. T...

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Detalles Bibliográficos
Autores principales: Kastberg, Louise La Barbera, Ard, Ryan, Jensen, Michael Krogh, Workman, Christopher T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Fungal Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512257/
https://www.ncbi.nlm.nih.gov/pubmed/37746199
http://dx.doi.org/10.3389/ffunb.2022.827704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512257/
https://www.ncbi.nlm.nih.gov/pubmed/37746199
http://dx.doi.org/10.3389/ffunb.2022.827704

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