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Burden Imposed by Heterologous Protein Production in Two Major Industrial Yeast Cell Factories: Identifying Sources and Mitigation Strategies
Production of heterologous proteins, especially biopharmaceuticals and industrial enzymes, in living cell factories consumes cellular resources. Such resources are reallocated from normal cellular processes toward production of the heterologous protein that is often of no benefit to the host cell. T...
Autores principales: | Kastberg, Louise La Barbera, Ard, Ryan, Jensen, Michael Krogh, Workman, Christopher T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512257/ https://www.ncbi.nlm.nih.gov/pubmed/37746199 http://dx.doi.org/10.3389/ffunb.2022.827704 |
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