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Nrf2 regulates iron-dependent hippocampal synapses and functional connectivity damage in depression

Neuronal iron overload contributes to synaptic damage and neuropsychiatric disorders. However, the molecular mechanisms underlying iron deposition in depression remain largely unexplored. Our study aims to investigate how nuclear factor-erythroid 2 (NF-E2)-related factor 2 (Nrf2) ameliorates hippoca...

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Detalles Bibliográficos
Autores principales: Zeng, Ting, Li, Junjie, Xie, Lingpeng, Dong, Zhaoyang, Chen, Qing, Huang, Sha, Xie, Shuwen, Lai, Yuqi, Li, Jun, Yan, Weixin, Wang, YuHua, Xie, Zeping, Hu, Changlei, Zhang, Jiayi, Kuang, Shanshan, Song, Yuhong, Gao, Lei, Lv, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512501/
https://www.ncbi.nlm.nih.gov/pubmed/37735410
http://dx.doi.org/10.1186/s12974-023-02875-x