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Calcineurin/NFATc3 pathway mediates myocardial fibrosis in diabetes by impairing enhancer of zeste homolog 2 of cardiac fibroblasts

BACKGROUND: Diabetes is associated with myocardial fibrosis, while the underlying mechanisms remain elusive. The aim of this study is to investigate the underlying role of calcineurin/nuclear factor of activated T cell 3 (CaN/NFATc3) pathway and the Enhancer of zeste homolog 2 (EZH2) in diabetes-rel...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Liu, Huan-Huan, Yang, Fan, Zhang, Zhi-Yuan, Wu, Ying, Li, Feng, Dang, Shi-Peng, Zhang, Zhen-Ye, Qian, Ling-Ling, Wang, Ru-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512648/
https://www.ncbi.nlm.nih.gov/pubmed/37735624
http://dx.doi.org/10.1186/s12872-023-03492-5