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DAP1 regulates osteoblast autophagy via the ATG16L1–LC3 axis in Graves’ disease-induced osteoporosis

OBJECTIVE: This study aimed to uncover a critical protein and its mechanisms in modulating autophagy in Graves’ disease (GD)-induced osteoporosis (OP). METHODS: We discovered the target protein, death-associated protein 1 (DAP1), using bone proteomics analysis. Furthermore, genetic overexpression an...

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Detalles Bibliográficos
Autores principales: Gao, Mingdong, Du, Zouxi, Dong, Qianqian, Su, Shan, Tian, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512661/
https://www.ncbi.nlm.nih.gov/pubmed/37735431
http://dx.doi.org/10.1186/s13018-023-04171-z