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DAP1 regulates osteoblast autophagy via the ATG16L1–LC3 axis in Graves’ disease-induced osteoporosis
OBJECTIVE: This study aimed to uncover a critical protein and its mechanisms in modulating autophagy in Graves’ disease (GD)-induced osteoporosis (OP). METHODS: We discovered the target protein, death-associated protein 1 (DAP1), using bone proteomics analysis. Furthermore, genetic overexpression an...
Autores principales: | Gao, Mingdong, Du, Zouxi, Dong, Qianqian, Su, Shan, Tian, Limin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512661/ https://www.ncbi.nlm.nih.gov/pubmed/37735431 http://dx.doi.org/10.1186/s13018-023-04171-z |
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