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A comparative analysis of gene and protein expression in chronic and acute models of photoreceptor degeneration in adult zebrafish

Background: Adult zebrafish are capable of photoreceptor (PR) regeneration following acute phototoxic lesion (AL). We developed a chronic low light (CLL) exposure model that more accurately reflects chronic PR degeneration observed in many human retinal diseases. Methods: Here, we characterize the m...

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Detalles Bibliográficos
Autores principales: Kramer, Ashley C., Carthage, Justin, Berry, Yasmeen, Gurdziel, Katherine, Cook, Tiffany A., Thummel, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512720/
https://www.ncbi.nlm.nih.gov/pubmed/37745292
http://dx.doi.org/10.3389/fcell.2023.1233269