Blocking cholesterol formation and turnover improves cellular and mitochondria function in murine heart microvascular endothelial cells and cardiomyocytes

Background: Statins and proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) are cornerstones of therapy to prevent cardiovascular disease, acting by lowering lipid concentrations and only partially identified pleiotropic effects. This study aimed to analyze impacts of atorvastatin and...

Descripción completa

Detalles Bibliográficos
Autores principales: Braczko, Alicja, Harasim, Gabriela, Kawecka, Ada, Walczak, Iga, Kapusta, Małgorzata, Narajczyk, Magdalena, Stawarska, Klaudia, Smoleński, Ryszard T., Kutryb-Zając, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512729/
https://www.ncbi.nlm.nih.gov/pubmed/37745244
http://dx.doi.org/10.3389/fphys.2023.1216267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512729/
https://www.ncbi.nlm.nih.gov/pubmed/37745244
http://dx.doi.org/10.3389/fphys.2023.1216267

Ejemplares similares