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Blocking cholesterol formation and turnover improves cellular and mitochondria function in murine heart microvascular endothelial cells and cardiomyocytes

Background: Statins and proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) are cornerstones of therapy to prevent cardiovascular disease, acting by lowering lipid concentrations and only partially identified pleiotropic effects. This study aimed to analyze impacts of atorvastatin and...

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Detalles Bibliográficos
Autores principales:	Braczko, Alicja, Harasim, Gabriela, Kawecka, Ada, Walczak, Iga, Kapusta, Małgorzata, Narajczyk, Magdalena, Stawarska, Klaudia, Smoleński, Ryszard T., Kutryb-Zając, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512729/ https://www.ncbi.nlm.nih.gov/pubmed/37745244 http://dx.doi.org/10.3389/fphys.2023.1216267

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