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Role of human epidermal growth factor receptor 3 in treatment resistance of anaplastic lymphoma kinase translocated non-small cell lung cancer

BACKGROUND: ALK tyrosine kinase inhibitors (TKI) have revolutionized the treatment of ALK+ non-small cell lung cancer (NSCLC), and therapy resistance occurs in virtually all patients. Multiple TKI resistance mechanisms have been characterized, including ERBB receptor coactivation. In this study, we...

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Detalles Bibliográficos
Autores principales: Honkanen, Tiia J, Luukkainen, Milla E K, Koivunen, Jussi P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512822/
https://www.ncbi.nlm.nih.gov/pubmed/37722715
http://dx.doi.org/10.1080/15384047.2023.2256906