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Heterogeneity characterization of hepatocellular carcinoma based on the sensitivity to 5-fluorouracil and development of a prognostic regression model

Background: 5-Fluorouracil (5-FU) is a widely used chemotherapeutic drug in clinical cancer treatment, including hepatocellular carcinoma (HCC). A correct understanding of the mechanisms leading to a low or lack of sensitivity of HCC to 5-FU-based treatment is a key element in the current personaliz...

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Detalles Bibliográficos
Autores principales: Gu, Xinyu, Li, Shuang, Ma, Xiao, Huang, Di, Li, Penghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512943/
https://www.ncbi.nlm.nih.gov/pubmed/37745063
http://dx.doi.org/10.3389/fphar.2023.1252805