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The Arf-GEF GBF1 undergoes multi-domain structural shifts to activate Arf at the Golgi

Golgi homeostasis require the activation of Arf GTPases by the guanine-nucleotide exchange factor requires GBF1, whose recruitment to the Golgi represents a rate limiting step in the process. GBF1 contains a conserved, catalytic, Sec7 domain (Sec7d) and five additional (DCB, HUS, HDS1-3) domains. He...

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Detalles Bibliográficos
Autores principales: Meissner, Justyna M., Akhmetova, Katarina, Szul, Tomasz, Viktorova, Ekaterina G., Sha, Bingdong, Bhatt, Jay M., Lee, Eunjoo J., Kahn, Richard A., Belov, George A., Chesnokov, Igor, Sztul, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512945/
https://www.ncbi.nlm.nih.gov/pubmed/37745300
http://dx.doi.org/10.3389/fcell.2023.1233272