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Plasma YKL-40 is associated with prognosis in patients with metastatic pancreatic cancer receiving immune checkpoint inhibitors in combination with radiotherapy

BACKGROUND: YKL-40, also known as chitinase-3-like protein 1 (CHI3L1), is a secreted glycoprotein produced by various cell types including stromal, immune, and cancer cells. It contributes to cancer progression through tumor-promoting inflammation and has been shown to inhibit the cytotoxicity of T...

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Detalles Bibliográficos
Autores principales: Johansen, Astrid Z., Novitski, Sif I., Hjaltelin, Jessica X., Theile, Susann, Boisen, Mogens K., Brunak, Søren, Madsen, Daniel H., Nielsen, Dorte L., Chen, Inna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513102/
https://www.ncbi.nlm.nih.gov/pubmed/37744345
http://dx.doi.org/10.3389/fimmu.2023.1228907