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Plasma YKL-40 is associated with prognosis in patients with metastatic pancreatic cancer receiving immune checkpoint inhibitors in combination with radiotherapy
BACKGROUND: YKL-40, also known as chitinase-3-like protein 1 (CHI3L1), is a secreted glycoprotein produced by various cell types including stromal, immune, and cancer cells. It contributes to cancer progression through tumor-promoting inflammation and has been shown to inhibit the cytotoxicity of T...
Autores principales: | Johansen, Astrid Z., Novitski, Sif I., Hjaltelin, Jessica X., Theile, Susann, Boisen, Mogens K., Brunak, Søren, Madsen, Daniel H., Nielsen, Dorte L., Chen, Inna M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513102/ https://www.ncbi.nlm.nih.gov/pubmed/37744345 http://dx.doi.org/10.3389/fimmu.2023.1228907 |
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