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Dexamethasone treatment of murine auditory hair cells and cochlear explants attenuates tumor necrosis factor-α-initiated apoptotic damage

The most common cause of sensorineural hearing loss is damage of auditory hair cells. Tumor necrosis factor-alpha (TNF-α) is closely associated with sensorineural hearing loss. The present study examined the preconditioning effect of dexamethasone (DEX) on TNF-α-induced ototoxicity in mouse auditory...

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Detalles Bibliográficos
Autores principales: Kang, Byung Chul, Yi, Junyeong, Kim, Song Hee, Pak, Jhang Ho, Chung, Jong Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513268/
https://www.ncbi.nlm.nih.gov/pubmed/37733709
http://dx.doi.org/10.1371/journal.pone.0291780