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Development of multi-drug resistance to anticancer drugs in HepG2 cells due to MRP2 upregulation on exposure to menthol

BACKGROUND: Menthol exerts relaxing, antibacterial, and anti-inflammatory activities, and is marketed as a functional food and therapeutic drug. AIM: In the present study, the effects of menthol on the expression of multidrug resistance associated protein 2 (MRP2) and its association with the cytoto...

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Detalles Bibliográficos
Autores principales: Nagai, Katsuhito, Tamura, Mayuko, Murayama, Ryuga, Fukuno, Shuhei, Ito, Takuya, Konishi, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513270/
https://www.ncbi.nlm.nih.gov/pubmed/37733713
http://dx.doi.org/10.1371/journal.pone.0291822