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Hyperglycemia increases SCO-spondin and Wnt5a secretion into the cerebrospinal fluid to regulate ependymal cell beating and glucose sensing

Hyperglycemia increases glucose concentrations in the cerebrospinal fluid (CSF), activating glucose-sensing mechanisms and feeding behavior in the hypothalamus. Here, we discuss how hyperglycemia temporarily modifies ependymal cell ciliary beating to increase hypothalamic glucose sensing. A high lev...

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Detalles Bibliográficos
Autores principales: Nualart, Francisco, Cifuentes, Manuel, Ramírez, Eder, Martínez, Fernando, Barahona, María José, Ferrada, Luciano, Saldivia, Natalia, Bongarzone, Ernesto R., Thorens, Bernard, Salazar, Katterine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513282/
https://www.ncbi.nlm.nih.gov/pubmed/37733692
http://dx.doi.org/10.1371/journal.pbio.3002308