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Modulation of cardiac cAMP signaling by AMPK and its adjustments in pressure overload-induced myocardial dysfunction in rat and mouse

The beta-adrenergic system is a potent stimulus for enhancing cardiac output that may become deleterious when energy metabolism is compromised as in heart failure. We thus examined whether the AMP-activated protein kinase (AMPK) that is activated in response to energy depletion may control the beta-...

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Detalles Bibliográficos
Autores principales: Garnier, Anne, Leroy, Jérôme, Deloménie, Claudine, Mateo, Philippe, Viollet, Benoit, Veksler, Vladimir, Mericskay, Mathias, Ventura-Clapier, Renée, Piquereau, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513315/
https://www.ncbi.nlm.nih.gov/pubmed/37733758
http://dx.doi.org/10.1371/journal.pone.0292015