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iHerd: an integrative hierarchical graph representation learning framework to quantify network changes and prioritize risk genes in disease
Different genes form complex networks within cells to carry out critical cellular functions, while network alterations in this process can potentially introduce downstream transcriptome perturbations and phenotypic variations. Therefore, developing efficient and interpretable methods to quantify net...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513318/ https://www.ncbi.nlm.nih.gov/pubmed/37695793 http://dx.doi.org/10.1371/journal.pcbi.1011444 |