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Glucose fluctuation promotes mitochondrial dysfunctions in the cardiomyocyte cell line HL-1

AIMS: Glycemic variability has been suggested as a risk factor for diabetes complications but the precise deleterious mechanisms remain poorly understood. Since mitochondria are the main source of energy in heart and cardiovascular diseases remain the first cause of death in patients with diabetes,...

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Detalles Bibliográficos
Autores principales: Mordel, Patrick, Fontaine, Fanny, Dupas, Quentin, Joubert, Michael, Allouche, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513336/
https://www.ncbi.nlm.nih.gov/pubmed/37733770
http://dx.doi.org/10.1371/journal.pone.0289475