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Non-gonadal somatic piRNA pathways ensure sexual differentiation, larval growth, and wing development in silkworms

PIWI-interacting RNAs (piRNAs) guide PIWI proteins to target transposons in germline cells, thereby suppressing transposon activity to preserve genome integrity in metazoans’ gonadal tissues. Piwi, one of three Drosophila PIWI proteins, is expressed in the nucleus and suppresses transposon activity...

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Detalles Bibliográficos
Autores principales: Kiuchi, Takashi, Shoji, Keisuke, Izumi, Natsuko, Tomari, Yukihide, Katsuma, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513339/
https://www.ncbi.nlm.nih.gov/pubmed/37733654
http://dx.doi.org/10.1371/journal.pgen.1010912