Cargando…

Novel bimodal TRBD1-TRBD2 rearrangements with dual or absent D-region contribute to TRB V-(D)-J combinatorial diversity

T-cell receptor (TR) diversity of the variable domains is generated by recombination of both the alpha (TRA) and beta (TRB) chains. The textbook process of TRB chain production starts with TRBD and TRBJ gene rearrangement, followed by the rearrangement of a TRBV gene to the partially rearranged D-J...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smirnova, Anastasia O., Miroshnichenkova, Anna M., Belyaeva, Laima D., Kelmanson, Ilya V., Lebedev, Yuri B., Mamedov, Ilgar Z., Chudakov, Dmitriy M., Komkov, Alexander Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513440/ https://www.ncbi.nlm.nih.gov/pubmed/37744336 http://dx.doi.org/10.3389/fimmu.2023.1245175

Ejemplares similares

A Feedback Regulatory Loop Involving dTrbd/dTak1 in Controlling IMD Signaling in Drosophila Melanogaster
por: Hua, Yongzhi, et al.
Publicado: (2022)

Corrigendum: A feedback regulatory loop involving dTrbd/dTak1 in controlling IMD signaling in Drosophila Melanogaster
por: Hua, Yongzhi, et al.
Publicado: (2022)

Identification of a TRBD zinc finger-interacting protein in Giardia duodenalis and its regulation of telomerase
por: Zheng, Jing-Tong, et al.
Publicado: (2019)

The use of non-functional clonotypes as a natural calibrator for quantitative bias correction in adaptive immune receptor repertoire profiling
por: Smirnova, Anastasia O, et al.
Publicado: (2023)

The Absence of Retroelement Activity Is Characteristic for Childhood Acute Leukemias and Adult Acute Lymphoblastic Leukemia
por: Urazbakhtin, Shamil, et al.
Publicado: (2022)

Method for identification of condition-associated public antigen receptor sequences
por: Pogorelyy, Mikhail V, et al.
Publicado: (2018)

Preparing Unbiased T-Cell Receptor and Antibody cDNA Libraries for the Deep Next Generation Sequencing Profiling
por: Mamedov, Ilgar Z., et al.
Publicado: (2013)

Huge Overlap of Individual TCR Beta Repertoires
por: Shugay, Mikhail, et al.
Publicado: (2013)

An advanced enrichment method for rare somatic retroelement insertions sequencing
por: Komkov, Alexander Y., et al.
Publicado: (2018)

Cummins recognises TRB for pandemic efforts
Publicado: (2021)

Precise tracking of vaccine-responding T cell clones reveals convergent and personalized response in identical twins
por: Pogorelyy, Mikhail V., et al.
Publicado: (2018)

Characterization of the ferret TRB locus guided by V, D, J, and C gene expression analysis
por: Gerritsen, Bram, et al.
Publicado: (2019)

Comparative Analysis of the TRB Locus in the Camelus Genus
por: Antonacci, Rachele, et al.
Publicado: (2019)

Control of Adipose Tissue Inflammation Through TRB1
por: Ostertag, Anke, et al.
Publicado: (2010)

Mother and Child T Cell Receptor Repertoires: Deep Profiling Study
por: Putintseva, Ekaterina V., et al.
Publicado: (2013)

Deep cfDNA fragment end profiling enables cancer detection
por: Zhitnyuk, Yulia V., et al.
Publicado: (2022)

Overview of the Germline and Expressed Repertoires of the TRB Genes in Sus scrofa
por: Massari, Serafina, et al.
Publicado: (2018)

Primary and secondary anti-viral response captured by the dynamics and phenotype of individual T cell clones
por: Minervina, Anastasia A, et al.
Publicado: (2020)

Lingual alveolar soft part sarcoma with absent TFE3 rearrangement
por: Alshahrani, Saeed, et al.
Publicado: (2020)

The Evidence for Increased L1 Activity in the Site of Human Adult Brain Neurogenesis
por: Kurnosov, Alexey A., et al.
Publicado: (2015)

Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor repertoires
por: Pogorelyy, Mikhail V., et al.
Publicado: (2017)

tcR: an R package for T cell receptor repertoire advanced data analysis
por: Nazarov, Vadim I., et al.
Publicado: (2015)

Quantitative tracking of T cell clones after haematopoietic stem cell transplantation
por: Mamedov, Ilgar Z, et al.
Publicado: (2011)

Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T-cell memory formation after mild COVID-19 infection
por: Minervina, Anastasia A, et al.
Publicado: (2021)

Whole-genome experimental identification of insertion/deletion polymorphisms of interspersed repeats by a new general approach
por: Mamedov, Ilgar Z., et al.
Publicado: (2005)

SeqURE – a new copy-capture based method for sequencing of unknown Retroposition events
por: Komkov, Alexander Y., et al.
Publicado: (2020)

Genomic analysis reveals extensive gene duplication within the bovine TRB locus
por: Connelley, Timothy, et al.
Publicado: (2009)

Data characterizing the genomic structure of the T cell receptor (TRB) locus in Camelus dromedarius
por: Antonacci, Rachele, et al.
Publicado: (2017)

High TRB3 expression induces chondrocyte autophagy and senescence in osteoarthritis cartilage
por: Gu, Yanqing, et al.
Publicado: (2022)

Optogenetic in vivo cell manipulation in KillerRed-expressing zebrafish transgenics
por: Teh, Cathleen, et al.
Publicado: (2010)

Reliable Flow-Cytometric Approach for Minimal Residual Disease Monitoring in Patients with B-Cell Precursor Acute Lymphoblastic Leukemia after CD19-Targeted Therapy
por: Mikhailova, Ekaterina, et al.
Publicado: (2022)

A high-throughput assay for quantitative measurement of PCR errors
por: Shagin, Dmitriy A., et al.
Publicado: (2017)

Apoptosis mechanisms induced by 15d-PMJ(2) in HCT116 colon cancer cells: insights into CHOP10/TRB3/Akt signaling
por: Albassam, Hussam, et al.
Publicado: (2023)

Stress-Inducible Caspase Substrate TRB3 Promotes Nuclear Translocation of Procaspase-3
por: Shimizu, Kouhei, et al.
Publicado: (2012)

The expansion of the TRB and TRG genes in domestic goats (Capra hircus) is characteristic of the ruminant species
por: Giannico, Francesco, et al.
Publicado: (2020)

Combinatorial DNA Rearrangement Facilitates the Origin of New Genes in Ciliates
por: Chen, Xiao, et al.
Publicado: (2015)

Inactivated tick-borne encephalitis vaccine elicits several overlapping waves of T cell response
por: Sycheva, Anastasiia L., et al.
Publicado: (2022)

Optimization of Low-Cost Ti-35421 Titanium Alloy: Phase Transformation, Bimodal Microstructure, and Combinatorial Mechanical Properties
por: Chen, Fuwen, et al.
Publicado: (2019)

Association of TRB3 Q84R polymorphism with polycystic ovary syndrome in Chinese women
por: Zhang, Xue, et al.
Publicado: (2011)

Mechanical Stretch Induces Apoptosis Regulator TRB3 in Cultured Cardiomyocytes and Volume-Overloaded Heart
por: Cheng, Wen-Pin, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_p8hvr8av5m4cleurqc516u8afp