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The prognostic value of whole-genome DNA methylation in response to Leflunomide in patients with Rheumatoid Arthritis

OBJECTIVE: Although Leflunomide (LEF) is effective in treating rheumatoid arthritis (RA), there are still a considerable number of patients who respond poorly to LEF treatment. Till date, few LEF efficacy-predicting biomarkers have been identified. Herein, we explored and developed a DNA methylation...

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Detalles Bibliográficos
Autores principales: Chen, Yulan, Wang, Qiao, Liu, Haina, Jin, Lei, Feng, Xin, Dai, Bingbing, Chen, Meng, Xin, Fangran, Wei, Tingting, Bai, Bingqing, Fan, Zhijun, Li, Jiahui, Yao, Yuxin, Liao, Ruobing, Zhang, Jintao, Jin, Xiangnan, Fu, Lingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513488/
https://www.ncbi.nlm.nih.gov/pubmed/37744384
http://dx.doi.org/10.3389/fimmu.2023.1173187