Genetic deletion of α7 nAChRs reduces hippocampal granule and pyramidal cell number in both sexes but impairs pattern separation in males only

INTRODUCTION: Neurogenesis within the dentate gyrus is thought to play an important role in cognitive processes such as reversal learning and pattern separation. The α7 nicotinic acetylcholine receptor (α7 nAChR) is expressed early in newly formed granule cells of the dentate gyrus, though its role...

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Detalles Bibliográficos
Autores principales: Letsinger, Ayland C., Nacer, Samir A., Stevanovic, Korey D., Larson, Gary J., DeFilipp, Jemma S., Cushman, Jesse D., Yakel, Jerrel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513752/
https://www.ncbi.nlm.nih.gov/pubmed/37746145
http://dx.doi.org/10.3389/fnins.2023.1244118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513752/
https://www.ncbi.nlm.nih.gov/pubmed/37746145
http://dx.doi.org/10.3389/fnins.2023.1244118

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