Cargando…

Phenotypic assay for cytotoxicity assessment of Balamuthia mandrillaris against human neurospheroids

INTRODUCTION: The phenotypic screening of drugs against Balamuthia mandrillaris, a neuropathogenic amoeba, involves two simultaneous phases: an initial step to test amoebicidal activity followed by an assay for cytotoxicity to host cells. The emergence of three-dimensional (3D) cell cultures has pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Whangviboonkij, Narisara, Pengsart, Worakamol, Chen, Zhenzhong, Han, Seokgyu, Park, Sungsu, Kulkeaw, Kasem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513763/
https://www.ncbi.nlm.nih.gov/pubmed/37744897
http://dx.doi.org/10.3389/fmicb.2023.1190530