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Phenotypic assay for cytotoxicity assessment of Balamuthia mandrillaris against human neurospheroids
INTRODUCTION: The phenotypic screening of drugs against Balamuthia mandrillaris, a neuropathogenic amoeba, involves two simultaneous phases: an initial step to test amoebicidal activity followed by an assay for cytotoxicity to host cells. The emergence of three-dimensional (3D) cell cultures has pro...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10513763/ https://www.ncbi.nlm.nih.gov/pubmed/37744897 http://dx.doi.org/10.3389/fmicb.2023.1190530 |