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Hepatic T-cell senescence and exhaustion are implicated in the progression of fatty liver disease in patients with type 2 diabetes and mouse model with nonalcoholic steatohepatitis

Immunosenescence and exhaustion are involved in the development and progression of type 2 diabetes (T2D) and metabolic liver diseases, including fatty liver, fibrosis, and cirrhosis, in humans. However, the relationships of the senescence and exhaustion of T cells with insulin resistance-associated...

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Detalles Bibliográficos
Autores principales: Sim, Byeong Chang, Kang, Yea Eun, You, Sun Kyoung, Lee, Seong Eun, Nga, Ha Thi, Lee, Ho Yeop, Nguyen, Thi Linh, Moon, Ji Sun, Tian, Jingwen, Jang, Hyo Ju, Lee, Jeong Eun, Yi, Hyon-Seung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514041/
https://www.ncbi.nlm.nih.gov/pubmed/37735474
http://dx.doi.org/10.1038/s41419-023-06146-8