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Thermodynamic forces from protein and water govern condensate formation of an intrinsically disordered protein domain

Liquid-liquid phase separation (LLPS) can drive a multitude of cellular processes by compartmentalizing biological cells via the formation of dense liquid biomolecular condensates, which can function as membraneless organelles. Despite its importance, the molecular-level understanding of the underly...

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Detalles Bibliográficos
Autores principales: Mukherjee, Saumyak, Schäfer, Lars V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514047/
https://www.ncbi.nlm.nih.gov/pubmed/37735186
http://dx.doi.org/10.1038/s41467-023-41586-y