Cargando…
Thermodynamic forces from protein and water govern condensate formation of an intrinsically disordered protein domain
Liquid-liquid phase separation (LLPS) can drive a multitude of cellular processes by compartmentalizing biological cells via the formation of dense liquid biomolecular condensates, which can function as membraneless organelles. Despite its importance, the molecular-level understanding of the underly...
Autores principales: | Mukherjee, Saumyak, Schäfer, Lars V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514047/ https://www.ncbi.nlm.nih.gov/pubmed/37735186 http://dx.doi.org/10.1038/s41467-023-41586-y |
Ejemplares similares
-
Spatially Resolved Hydration Thermodynamics in Biomolecular
Systems
por: Mukherjee, Saumyak, et al.
Publicado: (2022) -
Protein Condensate
Formation via Controlled Multimerization
of Intrinsically Disordered Sequences
por: Garabedian, Mikael V., et al.
Publicado: (2022) -
Determinants for intrinsically disordered protein recruitment into phase-separated protein condensates
por: Jo, Yongsang, et al.
Publicado: (2021) -
Intrinsically disordered regions and RNA binding domains contribute to protein enrichment in biomolecular condensates in Xenopus oocytes
por: O’Connell, Liam C., et al.
Publicado: (2023) -
Thermodynamic and sequential characteristics of phase separation and droplet formation for an intrinsically disordered region/protein ensemble
por: Chu, Wen-Ting, et al.
Publicado: (2021)