PDGFRA, KIT, and KDR Gene Amplification in Glioblastoma: Heterogeneity and Clinical Significance

Glioblastoma (GBM) is the most frequent tumor of the central nervous system, and its heterogeneity is a challenge in treatment. This study examined tumoral heterogeneity involving PDGFRA, KIT, and KDR gene amplification (GA) in 4q12 and its association with clinical parameters. Specimens from 22 GBM...

Descripción completa

Detalles Bibliográficos
Autores principales: Carlotto, Bianca Soares, Trevisan, Patricia, Provenzi, Valentina Oliveira, Soares, Fabiano Pasqualotto, Rosa, Rafael Fabiano Machado, Varella-Garcia, Marileila, Zen, Paulo Ricardo Gazzola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514169/
https://www.ncbi.nlm.nih.gov/pubmed/37610648
http://dx.doi.org/10.1007/s12017-023-08749-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514169/
https://www.ncbi.nlm.nih.gov/pubmed/37610648
http://dx.doi.org/10.1007/s12017-023-08749-y

Ejemplares similares