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MrgprA3-expressing pruriceptors drive pruritogen-induced alloknesis through mechanosensitive Piezo2 channel

Although touch and itch are coded by distinct neuronal populations, light touch also provokes itch in the presence of exogenous pruritogens, resulting in a phenomenon called alloknesis. However, the cellular and molecular mechanisms underlying the initiation of pruritogen-induced mechanical itch sen...

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Detalles Bibliográficos
Autores principales: Lu, Ping, Zhao, Yonghui, Xie, Zili, Zhou, Huan, Dong, Xinzhong, Wu, Gregory F., Kim, Brian S., Feng, Jing, Hu, Hongzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514240/
https://www.ncbi.nlm.nih.gov/pubmed/36961815
http://dx.doi.org/10.1016/j.celrep.2023.112283