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Stem cells-derived exosomes alleviate neurodegeneration and Alzheimer’s pathogenesis by ameliorating neuroinflamation, and regulating the associated molecular pathways

Amyloid beta (Aβ) aggregation and tau hyper phosphorylation (p-tau) are key molecular factors in Alzheimer’s disease (AD). The abnormal formation and accumulation of Aβ and p-tau lead to the formation of amyloid plaques and neurofibrillary tangles (NFTs) which ultimately leads to neuroinflammation a...

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Detalles Bibliográficos
Autores principales: Khan, Muhammad Imran, Jeong, Eun Sun, Khan, Muhammad Zubair, Shin, Jin Hyuk, Kim, Jong Deog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514272/
https://www.ncbi.nlm.nih.gov/pubmed/37735227
http://dx.doi.org/10.1038/s41598-023-42485-4