Cargando…

Stem cells-derived exosomes alleviate neurodegeneration and Alzheimer’s pathogenesis by ameliorating neuroinflamation, and regulating the associated molecular pathways

Amyloid beta (Aβ) aggregation and tau hyper phosphorylation (p-tau) are key molecular factors in Alzheimer’s disease (AD). The abnormal formation and accumulation of Aβ and p-tau lead to the formation of amyloid plaques and neurofibrillary tangles (NFTs) which ultimately leads to neuroinflammation a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khan, Muhammad Imran, Jeong, Eun Sun, Khan, Muhammad Zubair, Shin, Jin Hyuk, Kim, Jong Deog
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514272/ https://www.ncbi.nlm.nih.gov/pubmed/37735227 http://dx.doi.org/10.1038/s41598-023-42485-4

Ejemplares similares

Neuroprotective Effects of Green Tea Seed Isolated Saponin Due to the Amelioration of Tauopathy and Alleviation of Neuroinflammation: A Therapeutic Approach to Alzheimer’s Disease
por: Khan, Muhammad Imran, et al.
Publicado: (2022)

Therapeutic Effects of Saponins for the Prevention and Treatment of Cancer by Ameliorating Inflammation and Angiogenesis and Inducing Antioxidant and Apoptotic Effects in Human Cells
por: Khan, Muhammad Imran, et al.
Publicado: (2022)

Correction: Khan et al. Therapeutic Effects of Saponins for the Prevention and Treatment of Cancer by Ameliorating Inflammation and Angiogenesis and Inducing Antioxidant and Apoptotic Effects in Human Cells. Int. J. Mol. Sci. 2022, 23, 10665
por: Khan, Muhammad Imran, et al.
Publicado: (2023)

Green Tea Seed Isolated Theasaponin E1 Ameliorates AD Promoting Neurotoxic Pathogenesis by Attenuating Aβ Peptide Levels in SweAPP N2a Cells
por: Khan, Muhammad Imran, et al.
Publicado: (2020)

Pharmacological Approaches to Attenuate Inflammation and Obesity with Natural Products Formulations by Regulating the Associated Promoting Molecular Signaling Pathways
por: Khan, Muhammad Imran, et al.
Publicado: (2021)

The promising future of microalgae: current status, challenges, and optimization of a sustainable and renewable industry for biofuels, feed, and other products
por: Khan, Muhammad Imran, et al.
Publicado: (2018)

Crude microcystins extracted from Microcystis aeruginosa exert anti-obesity effects by downregulating angiogenesis and adipogenesis related signaling molecules in HUVEC and 3 T3-L1 cells
por: Khan, Muhammad Imran, et al.
Publicado: (2019)

Succinamide Derivatives Ameliorate Neuroinflammation and Oxidative Stress in Scopolamine-Induced Neurodegeneration
por: Iqbal, Sumbal, et al.
Publicado: (2020)

Multi-Platform Metabolomics Analyses Revealed the Complexity of Serum Metabolites in LPS-Induced Neuroinflammed Rats Treated with Clinacanthus nutans Aqueous Extract
por: Ahmad Azam, Amalina, et al.
Publicado: (2021)

Pretreatment optimization of the biomass of Microcystis aeruginosa for efficient bioethanol production
por: Khan, Muhammad Imran, et al.
Publicado: (2017)

The role of exosomes in the pathogenesis of Alzheimer’ disease
por: Xiao, Tingting, et al.
Publicado: (2017)

Advances in the Pathogenesis of Alzheimer’s Disease: Focusing on Tau-Mediated Neurodegeneration
por: Duan, Yale, et al.
Publicado: (2012)

Anthocyanins from Cornus kousa ethanolic extract attenuate obesity in association with anti-angiogenic activities in 3T3-L1 cells by down-regulating adipogeneses and lipogenesis
por: Khan, Muhammad Imran, et al.
Publicado: (2018)

Exosomes in Pathogenesis, Diagnosis, and Treatment of Alzheimer’s Disease
por: Jiang, Liqun, et al.
Publicado: (2019)

Green Tea Seed Isolated Saponins Exerts Antibacterial Effects against Various Strains of Gram Positive and Gram Negative Bacteria, a Comprehensive Study In Vitro and In Vivo
por: Khan, Muhammad Imran, et al.
Publicado: (2018)

An Insight into Cellular and Molecular Mechanisms Underlying the Pathogenesis of Neurodegeneration in Alzheimer’s Disease
por: Ratan, Yashumati, et al.
Publicado: (2023)

The Role of Exosomes as Mediators of Neuroinflammation in the Pathogenesis and Treatment of Alzheimer’s Disease
por: Weng, Shiting, et al.
Publicado: (2022)

Role of Exosomes in the Pathogenesis and Theranostic of Alzheimer’s Disease and Parkinson’s Disease
por: He, Aojie, et al.
Publicado: (2023)

Intermittent fasting positively modulates human gut microbial diversity and ameliorates blood lipid profile
por: Khan, Muhammad Nadeem, et al.
Publicado: (2022)

Microglia in Alzheimer's Disease: A Favorable Cellular Target to Ameliorate Alzheimer's Pathogenesis
por: Sumsuzzman, Dewan Md., et al.
Publicado: (2022)

Fibroblast growth factor 21 ameliorates neurodegeneration in rat and cellular models of Alzheimer’s disease
por: Chen, Song, et al.
Publicado: (2019)

Editorial: The role of exosomes in neuroinflammation and neurodegeneration
por: Wang, Yi, et al.
Publicado: (2022)

Attenuation and Production of the Amphotericin B-Resistant Leishmania tropica Strain
por: Khan, Imran, et al.
Publicado: (2016)

Molecular and Cellular Basis of Neurodegeneration in Alzheimer’s Disease
por: Jeong, Sangyun
Publicado: (2017)

Impact of AKT1 Polymorphism on DNA Damage, BTG2 Expression, and Risk of Colorectal Cancer Development
por: Zubair, Hina, et al.
Publicado: (2022)

Mesenchymal Stem Cell-Derived Exosomes Ameliorate Alzheimer’s Disease Pathology and Improve Cognitive Deficits
por: Chen, Yi-An, et al.
Publicado: (2021)

The roles of lipid and glucose metabolism in modulation of β-amyloid, tau, and neurodegeneration in the pathogenesis of Alzheimer disease
por: Sato, Naoyuki, et al.
Publicado: (2015)

Enhancing the Feasibility of Microcystis aeruginosa as a Feedstock for Bioethanol Production under the Influence of Various Factors
por: Khan, Muhammad Imran, et al.
Publicado: (2016)

Human neural stem cells alleviate Alzheimer-like pathology in a mouse model
por: Lee, Il-Shin, et al.
Publicado: (2015)

Molecular mechanisms of neurodegeneration in the entorhinal cortex that underlie its selective vulnerability during the pathogenesis of Alzheimer's disease
por: Olajide, Olayemi Joseph, et al.
Publicado: (2021)

Increased Microglial Exosomal miR-124-3p Alleviates Neurodegeneration and Improves Cognitive Outcome after rmTBI
por: Ge, Xintong, et al.
Publicado: (2020)

Metabolism-Centric Overview of the Pathogenesis of Alzheimer's Disease
por: Kang, Somang, et al.
Publicado: (2017)

An overview of viral mutagenesis and the impact on pathogenesis of SARS-CoV-2 variants
por: Khan, Muhammad Zafar Irshad, et al.
Publicado: (2022)

Kynurenines, neurodegeneration and Alzheimer’s disease
por: Kincses, Zsigmond Tamas, et al.
Publicado: (2010)

Alleviation of renal ischemia/reperfusion injury by exosomes from induced pluripotent stem cell-derived mesenchymal stem cells
por: Lim, Sun Woo, et al.
Publicado: (2022)

Chemical Characterization and Ameliorating Effect of Centratherum anthelminticum Extract against Polycystic Ovary Syndrome in Wistar Rats
por: Shoaib, Moonis, et al.
Publicado: (2023)

Genetic Screening and Expression Analysis of Psychrophilic Bacillus spp. Reveal Their Potential to Alleviate Cold Stress and Modulate Phytohormones in Wheat
por: Zubair, Muhammad, et al.
Publicado: (2019)

Melatonin Ameliorates Thermotolerance in Soybean Seedling through Balancing Redox Homeostasis and Modulating Antioxidant Defense, Phytohormones and Polyamines Biosynthesis
por: Imran, Muhammad, et al.
Publicado: (2021)

Molecular Pathogenesis of Polymerase Gamma–Related Neurodegeneration
por: Tzoulis, Charalampos, et al.
Publicado: (2014)

Potential role of exosome in post-stroke reorganization and/or neurodegeneration
por: Azizi, Fateme, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_c4ff8c68hrg3olr43lgj6vhiru