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Tauopathy promotes spinal cord-dependent production of toxic amyloid-beta in transgenic monkeys
Tauopathy, characterized by the hyperphosphorylation and accumulation of the microtubule-associated protein tau, and the accumulation of Aβ oligomers, constitute the major pathological hallmarks of Alzheimer’s disease. However, the relationship and causal roles of these two pathological changes in n...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514290/ https://www.ncbi.nlm.nih.gov/pubmed/37735155 http://dx.doi.org/10.1038/s41392-023-01601-6 |