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U2AF1 pathogenic variants in myeloid neoplasms and precursor states: distribution of co-mutations and prognostic heterogeneity

We have previously recognized the genotypic and prognostic heterogeneity of U2AF1 mutations (MT) in myelofibrosis (MF) and myelodysplastic syndromes (MDS). In the current study, we considered 179 U2AF1-mutated patients with clonal cytopenia of undetermined significance (CCUS; n = 22), MDS (n = 108),...

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Detalles Bibliográficos
Autores principales: Badar, Talha, Vanegas, Yenny A. Moreno, Nanaa, Ahmad, Foran, James M., Al-Kali, Aref, Mangaonkar, Abhishek, Murthy, Hemant, Alkhateeb, Hassan B., Viswanatha, David, He, Rong, Shah, Mithun, Yi, Cecilia Arana, Litzow, Mark R., Gangat, Naseema, Tefferi, Ayalew, Patnaik, Mrinal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514309/
https://www.ncbi.nlm.nih.gov/pubmed/37735430
http://dx.doi.org/10.1038/s41408-023-00922-7