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Signal-noise metrics for RNA binding protein identification reveal broad spectrum protein-RNA interaction frequencies and dynamics

Recent efforts towards the comprehensive identification of RNA-bound proteomes have revealed a large, surprisingly diverse family of candidate RNA-binding proteins (RBPs). Quantitative metrics for characterization and validation of protein-RNA interactions and their dynamic interactions have, howeve...

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Detalles Bibliográficos
Autores principales: Kristofich, JohnCarlo, Nicchitta, Christopher V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514315/
https://www.ncbi.nlm.nih.gov/pubmed/37735163
http://dx.doi.org/10.1038/s41467-023-41284-9