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The cGAS-STING pathway-dependent sensing of mitochondrial DNA mediates ocular surface inflammation

The innate immune response is the main pathophysiological process of ocular surface diseases exposed to multiple environmental stresses. The epithelium is central to the innate immune response, but whether and how innate immunity is initiated by ocular epithelial cells in response to various environ...

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Detalles Bibliográficos
Autores principales: Ouyang, Weijie, Wang, Shoubi, Yan, Dan, Wu, Jieli, Zhang, Yunuo, Li, Wei, Hu, Jiaoyue, Liu, Zuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514335/
https://www.ncbi.nlm.nih.gov/pubmed/37735446
http://dx.doi.org/10.1038/s41392-023-01624-z